Sunday, May 2, 2010





Artificial selection has resulted in plants that are more disease-resistant, cows that produce more milk, and racehorses that run faster. One must wonder what will come next. In the blog entry answer the following question - under what circumstances should humans be artificially selecting plants or animals, if any?







What is Artificial Selection, and how is it being used?

Artificial selection, or selective breeding, is genetic selection which is controlled by people, within a genetically diverse population. Artificial selection is the basis of both domestication, and modern plant and animal breeding. It’s being used to breed plants and animals that contain
all of the genetic traits that we desire, and none of the ones that we don’t. Upon first contact with the subject you might assume that artificial selection is the opposite of natural selection, however it’s not really a simple case of black and white. It’s “artificial” selection, not because it makes use of genetic engineering and tampering, but because there is an influence on the types of species that breed. Artificial selection is most prominently present in the case of domesticated animals, such as dogs. In this case, breeders would simply promote breeding between
dogs having desirable characteristics, and discourage breeding between dogs that do not. Evolutionary biologists view domesticated breeding as a type of natural selection, but with adaptive change in organisms under human control.

The proposal of this idea
The notion of artificial selection was expressed by the Persian polymath Abu Rayhan Biruni in the 11th century. He suggested the idea in his book entitled India, and gave various examples of it, some of which are described in the following statement by Biruni:
“The agriculturist selects his corn, letting grow as much as he requires, and tearing out the remainder. The forester leaves those branches which he perceives to be excellent, whilst he cuts away all others. The bees kill those of their kind who only eat, but do not work in their beehive.”

Another prominent figure that spoke of artificial selection was Charles Darwin, who used the term twice in his book, On the Origin of Species. In the first reference, he wrote about the complex and beautiful things he believes that humans can create through artificial selection. In the second reference, he used the term to describe the reasons for differences in animal breeds in countries with different development levels. Darwin, however, did not clearly define the term in his book.









The Cons
Inbred offspring are one of the potential dangers of too much artificial selection. Some traits are so rare that they may only exist in one or two family lines. If the trait is recessive, two relatives may have to be bred together in order for the trait to be expressed, or visible. In animals, this can result in genetic defects and other serious problems.
In many cases, artificial selection has been used for aesthetic improvements, while hurting the subject’s ability to function or survive. The domestication cycle of dogs being bred by their owners in order to emphasize less-aggressive traits has gone on for thousands of years, and has resulted in hundreds of different breeds that look almost nothing like their ancestor (grey wolf). Dairy cattle are also bred using artificial selection in hopes of producing more milk, but some lines now suffer from increased infections and fertility problems. Persian cats that are bred for extremely flat faces often develop respiratory problems and may have trouble eating. All of the listed traits that are bred for do not help the animals survive in the wild, but do make them more desirable to their owners.


When you hear that artificial selection can help us to create cows that produce better milk, racehorses that run faster, or dogs that are less aggressive and more obedient, your first thought will most likely be that it’s a great method of breeding, and you’ll support it entirely (unless, for some reason, you’re against progress). However, like all great things, we must still be conscientious and aware of the problems that it could cause. Not many people are aware of the seriousness of artificial selection and I believe that until it is known to more people, the only thing it can do is cause problems in the future and get way out of hand. I personally think that "oh natural" is the way to go. I Don't think it is necessary to change the growth or breeding patterns of food or animals in any way. I think science is way ahead of our time and things are getting a little bit too carried away these days.






Sources - daniella's bio blog

http://www.opbf.org/open-plant-breeding/glossary/a
http://en.wikipedia.org/wiki/Artificial_selection
http://www.wisegeek.com/what-is-artificial-selection.htm

Sunday, January 10, 2010

Designer Babies

"Designer Babies" is the term being used by the media to describe the future of modifying or selecting our children's genes for desirable characteristics (medical and cosmetic). Are things getting out of hand with our research into genetic processes? In this blog investigate social and ethical implications of this research and technologies that have been developed from it.






What is a designer baby? A baby whose genetic makeup has been artificially selected by genetic engineering combined with in vitro fertilisation to ensure the presence or absence of particular genes or characteristics.I was in a certain state of shock when i first found out about this form of cloning. Babies are created by a man and a women,not by any Doctors and most certainly not in a little round dish.To design your baby like you would a room in your house or a baby doll is unnecessary and wrong. Call me crazy, but this all sounds a little to out of this world!






















Advanced reproductive techniques involve using InVitro Fertilisation or IVF to fertilise eggs with sperm in 'test-tubes' outside the mother's body in a laboratory. These techniques allow doctors and parents to reduce the chance that a child will be born with a genetic disorder. At the moment it is only legally possible to carry out two types of advanced reproductive technologies on humans. The first involves choosing the type of sperm that will fertilise an egg: this is used to determine the sex and the genes of the baby. The second technique screens embryos for a genetic disease: only selected embryos are implanted back into the mother's womb. This is called Pre-implantation Genetic Diagnosis (PGD).Advances in genetics have allowed parents and doctors to genetically screen embryos for any genetic disorders. This allows doctors to screen the embryos making it possible to eliminate genes associated with several genetic defects and illnesses. This modern technique has brought out arguments about ethical concerns and cause many people to really analyze the pros and cons of this medical advancement.



Here is a video of Professor Lee Silver explaining the process of Pre-implantation in depth








ADVANTAGES OF PRE-IMPLANTATION
-Genetic screening can reduce the baby's chances of being born with several serious diseases like Down Syndrome, Family hypercholesterolemia, rare blood disorders such as Diamond Black fan Anaemia, etc.

reading this makes me think of the book My Sisters Keeper by: Jodi Picoult. In this book Anna is created to save her sister Kate's life. At the age of 5 Kate was diagnosed with Leukemia and in order to keep her alive, Her parents created Anna. By the process of Pre-implantation, Anna was conceived as a bone marrow match for her sister.


In the process of doing research on this topic, i was able to find a real life example of a child being created by the same process as well as for the same reasons. Adam Nash was created in 2000 and was the worlds first Designer baby. He was created by pre-implantation to save his dying sisters life. Here are some links for article's on the birth of Adam and further details






DISADVANTAGES OF PRE-IMPLANTATION

-Other than eliminating genetic diseases, The process of Pre-implantation allows parents to choose the gender, eye, skin and hair color of the baby and Various other physical traits such as intelligence, beauty, height, stopping a propensity towards obesity, freedom from mental illnesses, athletic ability, etc. This is unnecessary and coasts about 18,000 a baby.
- Many think that It is unethical to create designer babies with enhanced physical ability and appearance and will divorce the procreation from the act of sexual congress.
- The Level in Biodiversity will plummet and in the end can result in long term disaster.
-Being able to create the perfect child with high intelligence, great athleticism, and good looks would give parents a certain control that will be taken advantage of. This would take away from the child’s say in their own life as well as the child’s freedom to develop the skills in which they would need to succeed in whatever paths they may choose.
- This would cause huge problems in today’s society. Discrimination would just become a bigger problem as most would be created without any genetic defects. Due to the coast of pre-implantation, not everyone would be able to benefit from its advantages. In the end this will cause a wall to build between those who are genetically perfect and those who are not. this could lead to discrimination of both gender and race.











This kind of technology is to much for our society to handle at this point in time. There are many way's in which this can cause our society to break apart and possibly become more chaotic then it already is. Due to the fact that this is a very expensive procedure, the division between those who can afford it and those who cant would be a huge problem. there would be new classes of rich and poor and those who were not genetically engineered would be discriminated against. We as a society have grown together accepting the fact that our world is full of imperfections. When we start taking away those imperfections, we will forget the true meaning of anything other then people's looks and metal, and physical capabilities.



I Personally think this is ridiculous and that science is getting way to out of hand. The point of having a baby is the fact that it is made from the chromosome's of the mother and the father. When I think about this I imagine a couple sitting in an office and choosing their child characteristics from a book! To me, the beauty of having a child is the surprise of finally seeing what they look like when they are born, teaching then how to be good at sports and pressuring them to study and become successful. With the advances in science and pre-implantation, these things would already be inherited and the connection between the parent and child would be lost. This genetic process defeats the purpose of a family and ones personal, physical and mental development. Its time to wake up and realise that there are much bigger problems that should be solved before we start making the creation of the "perfect child" our number one priority.







Sources